Karina Serban, MD

Karina Serban, MD
Associate Professor of Medicine

UF Health Pulmonary – Medical Specialties – Medical Plaza

Email: karina.serban@medicine.ufl.edu
TEL: 352-273-8737

MDCarol Davila University of Medicine and Pharmacy, Bucharest, Romania Medicine
ResidencyThe Chicago Medical School, Rosalind Franklin University of
Medicine & Science, Internal Medicine Program, Chicago, IL
Internal Medicine
FellowshipIndiana University Purdue University Indianapolis, INPulmonary & Critical Care Medicine


  • Pulmonary Medicine
  • Critical Care Medicine

Clinical Interests:

  • Alpha-1 Antitrypsin Deficiency
  • COPD
  • Emphysema
  • Combined pulmonary fibrosis emphysema syndrome
  • Rare lung disorders

Research Interests:

Board Certifications:

  • Pulmonary Medicine
  • Critical Care Medicine

Professional Societies:

  • American Thoracic Society (ATS)
  • European Respiratory Society (ERS)

Honors and Awards:

  • 2009 ATS Resident Travel Award
  • 2010 ATS Travel Award
  • 2012 IUPUI Department of Medicine Fifteenth Annual Resident and Fellow Research Forum and Competition
  • 2013 IUPUI Department of Medicine Sixteen Annual Resident and Fellow Research Forum and Competition
  • 2014 Alpha-1 Foundation The inaugural Gordon L. Snider Scholar Award
  • 2015 National Jewish Health Department of Medicine / MOOR Research Retreat Competition
  • 2016 ATS Abstract Scholarship
  • 2016 Alpha-1 Antitrypsin Laurell’s Training Award

Active Grants:

  • K08 HL141770-01A1 Mentored Clinical Scientist Research Career Development Award, November 2023- Title: Mannose Binding Lectin-Dependent Complement Activation in Emphysema
  • R01 HL166828-01 Research Project Grant, June 2027- Title: Decay Accelerating Factor (CD55) Deficiency Facilitates Lectin Pathway Mediated AT2 Cell Dysfunction in Cigarette Smoke-induced Emphysema


  • Mikosz A, Ni K, Gally F, Pratte KA, Winfree S, Lin Q, Echelman I, Wetmore B, Cao D, Justice MJ, Sandhaus RA, Maier L, Strange C, Bowler RP, Petrache I, Serban KA. Alpha-1 antitrypsin inhibits fractalkine-mediated monocyte-lung endothelial cell interactions. Am J Physiol Lung Cell Mol Physiol. 2023 Oct 10. doi: 10.1152/ajplung.00023.2023. Epub ahead of print. PMID: 37814796.
  • Serban KA, Pratte KA, Strange C, Sandhaus RA, Turner AM, Beiko T, Spittle DA, Maier L, Hamzeh N, Silverman EK, Hobbs BD, Hersh CP, DeMeo DL, Cho MH, Bowler RP. Unique and shared systemic biomarkers for emphysema in Alpha-1 Antitrypsin deficiency and chronic obstructive pulmonary disease. EBioMedicine. 2022 Sep 22;84:104262. doi: 10.1016/j.ebiom.2022.104262. PMID: 36155958; PMCID: PMC9507992.
  • Goel K, Serban KA. The multifaceted protease-anti-protease imbalance in COVID-19. EBioMedicine. 2022;78:103973. doi:10.1016/j.ebiom.2022.103973
  • Goel K, Maleki-Fischbach M, George MP, Kim D, Richards J, Wise RA, Serban KA. A 56-Year-Old Man with Emphysema, Rash, and Arthralgia. Chest. 2021 Nov;160(5):e513-e518. doi: 10.1016/j.chest.2021.06.045. PMID: 34743855; PMCID: PMC8727885.
  • I Petrache, KA Serban, Can Metformin downshift the gears of aging to slow emphysema progression? Am J Respir Crit Care Med. 2021 Sep 15;204(6):621-622. doi: 10.1164/rccm.202105-1273ED. PMID: 34191690.
  • KA Serban, KA Pratte, RP. Bowler, Protein biomarkers for COPD outcomes, CHEST, 2021 Jan 9, https://doi.org/10.1016/j.chest.2021.01.004
  • Berdyshev EV, Serban KA, Schweitzer KS, et al Ceramide and sphingosine-1 phosphate in COPD lungs, Thorax, Published Online First: 29 January 2021. doi: 10.1136/thoraxjnl-2020-215892.
  • Schweitzer, K; Crue, T; Nall, J; Foster, D; Sajuthi, S; Correll, K; Nakamura, M; Everman, J; Seibold, M; Bridges, J; Serban, K; Downey, G; Chu, H; Petrache, I, Influenza virus infection increases ACE2 expression and shedding in human small airway epithelial cells, Eur Respir J 2021, doi.org/10.1183/13993003.03988-2020.
  • Serban KA, Mikosz A, Strange C, Janciauskiene SM, Stolk J, Jonigk D, Sandhaus RA, Petrache I. Lectin Complement Pathway in Emphysema, Am J Respir Crit Care Med. 2019 Mar 1;199(5):659-661. doi: 10.1164/rccm.201807-1380LE, PMID: 30557515.
  • Serban KA, Rezania S, Petrusca DN, Poirier C, Cao D, Justice MJ, Patel M, Tsvetkova I, Kamocki K, Van Demark M, Schweitzer KS, Cardoso A, Carlesso N, Hubbard WC, Dragnea B, Berdyshev EV, McClintock J, and Petrache I, “Structural and functional characterization of endothelial microparticles released by cigarette smoke”, Sci Rep. 2016 Aug 17;6:31596, PMID: 27530098.

For a complete list of publications: