division of pulmonary, critical care & sleep medicine
Scindia Lab
research
Yogesh Scindia, PhD
Associate Professor of Medicine (Tenured)
Yogesh.scindia@medicine.ufl.edu
Overview
The Scindia Lab studies how iron dysregulation and ferroptosis (an iron-dependent form of regulated necrosis) link autoimmunity, with a focus on lupus and lupus nephritis, and fungal infections. Their work integrates immunology, microbiology, and translational science to uncover shared pathogenic mechanisms and leverage them to identify actional therapeutic targets.
Focus Areas
- Autoimmunity and Iron
- Lupus and Lupus Nephritis
- Fungal Infections and Iron
- Ferroptosis
Lab Staff
Biological Scientist II
Divya Katikaneni
graduate assistant
Tanmay Arekar
Graduate Assistant
Leena Al Hraki
Graduate Assistant
Thrisha Acharya
Publication Highlights
- Essential role of hepcidin in host resistance to disseminated candidiasis
- Vamifeport, a clinical stage oral ferroportin inhibitor, alleviates murine lupus nephritis: A pilot study
- Functional consequence of Iron dyshomeostasis and ferroptosis in systemic lupus erythematosus and lupus nephritis
- Kidney tubular epithelial cell ferroptosis links glomerular injury to tubulointerstitial pathology in lupus nephritis
- Modulation of iron homeostasis with hepcidin ameliorates spontaneous murine lupus nephritis
- Iron metabolism and ferroptosis: druggable targets to delay the progression of lupus nephritis
For more PI Publications please follow the links below